Flocculation protein FLO11 (P08640)

Identification
NameFlocculation protein FLO11
Synonyms
  • Flo11p
  • Flocculin-11
  • Mucin-like protein 1
Gene NameFLO11
Enzyme ClassNot Available
Biological Properties
General Functionsingle-species surface biofilm formation
Specific FunctionCell wall protein that participates in adhesive cell-cell interactions during yeast flocculation, a reversible, asexual and Ca(2+)-dependent process in which cells adhere to form aggregates (flocs) consisting of thousands of cells. Also involved in cell-substrate adhesion, haploid invasive growth, diploid pseudohyphae formation and biofilm (flor) development. The precise mechanism by which this protein mediates adhesion is unclear but may involve homotypic binding. Adhesive activity is inhibited by mannose, but not by glucose, maltose, sucrose or galactose.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: starvation test 1PW003483 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
invasive growth in response to glucose limitation
pseudohyphal growth
anchored component of membrane
cell wall
extracellular region
plasma membrane
cell adhesion involved in single-species biofilm formation
coflocculation
filamentous growth
flocculation
single organismal cell-cell adhesion
single-species biofilm formation on inanimate substrate
single-species surface biofilm formation
cellular bud neck
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>4104 bp ATGCAAAGACCATTTCTACTCGCTTATTTGGTCCTTTCGCTTCTATTTAACTCGGCTTTG GGTTTTCCAACTGCACTAGTTCCAAGAGGATCCTCCGAAGGAACTAGCTGTAATTCTATC GTTAATGGCTGTCCCAACTTAGACTTCAATTGGCACATGGACCAGCAAAATATCATGCAG TATACTTTGGATGTGACTTCCGTTTCTTGGGTTCAAGACAACACATACCAAATCACTATT CATGTCAAAGGTAAAGAAAATATTGACCTGAAGTATCTATGGTCTTTGAAAATCATTGGT GTCACTGGTCCAAAAGGTACCGTCCAACTATACGGTTACAACGAAAATACCTATTTGATT GACAACCCAACTGATTTCACAGCCACTTTTGAAGTTTATGCCACACAAGATGTCAACAGC TGTCAGGTGTGGATGCCTAACTTCCAAATTCAATTCGAGTATTTGCAAGGTAGTGCCGCT CAATATGCAAGCTCCTGGCAATGGGGAACTACATCTTTTGATTTGTCTACTGGTTGTAAC AACTATGACAATCAAGGCCACTCTCAAACGGATTTCCCAGGCTTCTATTGGAACATAGAT TGTGACAATAATTGTGGCGGTACGAAGTCATCTACCACTACATCTAGCACTTCCGAGTCA TCTACCACTACATCTAGCACTTCCGAGTCATCTACCACTACATCTAGCACTTCCGAGTCA TCTACCACTACATCTAGCACTTCCGAGTCATCTACATCATCATCAACCACCGCTCCTGCT ACACCAACCACTACCTCATGCACTAAGGAAAAGCCTACACCCCCAACCACTACCTCATGC ACAAAGGAAAAGCCTACACCTCCTCATCACGACACCACTCCATGTACAAAGAAGAAAACT ACCACATCTAAGACATGCACTAAGAAGACTACTACTCCAGTACCAACCCCATCAAGCTCT ACTACTGAAAGTTCTTCTGCTCCAGTACCAACTCCATCCAGCTCTACTACTGAAAGCTCT TCTGCTCCAGTAACCAGCTCTACCACTGAAAGCTCTTCTGCTCCAGTACCAACCCCATCA AGCTCTACTACTGAAAGCTCTTCTGCTCCAGTAACCAGCTCTACCACTGAAAGCTCTTCT GCTCCAGTAACCAGCTCTACCACTGAAAGCTCTTCTGCTCCAGTACCAACTCCATCCAGC TCTACTACTGAAAGCTCTTCTGCTCCAGTAACCAGCTCTACCACTGAAAGCTCTTCTGCT CCAGTAACCAGCTCTACCACTGAAAGCTCTTCTGCTCCAGTAACCAGCTCTACCACTGAA AGCTCTTCTGCTCCAGTAACCAGCTCTACCACTGAAAGCTCTTCTGCTCCAGTACCAACT CCATCCAGCTCTACTACTGAAAGCTCTTCTGCTCCAGTAACCAGCTCTACCACTGAAAGC TCTTCTGCTCCAGTACCAACTCCATCCAGCTCTACTACTGAAAGCTCTTCTGCTCCAGTA ACCAGCTCTACCACTGAAAGCTCTTCTGCTCCAGTACCAACTCCATCCAGCTCTACTACT GAAAGCTCTTCTGCTCCAGCTCCAACCCCATCAAGCTCCACCACTGAAAGCTCTTCTGCT CCAGTAACCAGCTCTACCACTGAAAGCTCTTCTGCTCCAGTACCAACTCCATCCAGCTCT ACTACTGAAAGCTCTTCTACTCCAGTAACCAGCTCCACCACTGAAAGCTCTTCTGCTCCA GTGCCAACTCCATCAAGCTCTACTACTGAAAGCTCTTCTGCTCCAGTACCAACTCCATCA AGCTCTACTACTGAAAGCTCTTCTGCTCCAGCTCCAACCCCATCAAGCTCTACTACTGAA AGCTCTTCTGCTCCAGTAACCAGCTCTACCACTGAAAGCTCTTCTGCTCCAGTACCAACT CCATCCAGCTCTACTACTGAAAGCTCTTCTGCTCCAGTACCAACCCCATCCAGCTCTACT ACTGAAAGCTCTTCTGCTCCAGTACCAACTCCATCCAGCTCTACTACTGAAAGCTCTTCT GCTCCAGTAACCAGCTCTACCACTGAAAGCTCTTCTGCTCCAGTAACCAGCTCTACCACT GAAAGCTCTTCTGCTCCAGTACCAACTCCATCCAGCTCTACTACTGAAAGCTCTTCTGCT CCAGTACCAACTCCATCCAGCTCTACTACTGAAAGCTCTTCTGCTCCAGTACCAACTCCA TCCAGCTCTACTACTGAAAGCTCTTCTGCTCCAGTAACCAGCTCTACCACTGAAAGCTCT TCTGCTCCAGTACCAACTCCATCCAGCTCTACTACTGAAAGCTCTTCTGCTCCAGTGCCA ACTCCATCCAGCTCTACTACCGAAAGCTCTTCTGCTCCAGTACCAACCCCATCAAGCTCT ACTACTGAAAGCTCTGTAGCACCAGTACCAACCCCATCTTCCTCTAGCAACATCACTTCC TCCGCTCCATCTTCAACCCCATTCAGCTCTAGCACTGAAAGCTCTTCTGTTCCAGTACCA ACCCCATCAAGCTCTACTACTGAAAGCTCTTCTGCTCCAGTATCCAGCTCCACCACTGAA AGCTCTGTAGCACCAGTACCAACCCCATCTTCCTCTAGCAACATCACTTCCTCCGCTCCA TCTTCAATTCCATTCAGCTCTACTACTGAAAGCTTTTCTACTGGCACTACTGTCACTCCA TCATCATCCAAATACCCTGGCAGTCAAACAGAAACCTCTGTTTCTTCTACAACCGAAACT ACCATTGTTCCAACTAAAACTACGACTTCTGTCACTACACCATCAACAACCACTATTACC ACTACGGTTTGCTCTACAGGAACAAACTCTGCCGGTGAAACTACCTCTGGATGCTCTCCA AAGACCGTTACAACTACTGTTCCAACTACAACTACGACTTCTGTCACTACATCATCAACA ACCACTATTACTACTACAGTTTGCTCTACAGGAACAAACTCTGCCGGTGAAACTACCTCT GGATGCTCTCCAAAGACCATTACAACTACTGTTCCATGTTCAACCAGTCCAAGCGAAACC GCCTCGGAATCAACAACCACTTCACCTACCACACCTGTAACTACAGTTGTCTCAACCACC GTCGTTACTACTGAGTATTCTACTAGTACAAAACCAGGTGGTGAAATTACAACTACATTT GTCACCAAAAACATTCCAACCACTTACCTAACCACAATTGCTCCAACTCCATCAGTCACT ACGGTTACCAATTTCACCCCAACCACTATTACTACTACGGTTTGCTCTACAGGTACAAAC TCTGCCGGTGAAACTACCTCTGGATGCTCTCCAAAGACTGTCACAACCACTGTTCCTTGT TCAACTGGTACTGGCGAATACACTACTGAAGCTACCACCCTTGTTACAACAGCTGTCACA ACCACCGTTGTTACCACTGAATCCTCTACGGGTACTAACTCCGCTGGTAAGACGACAACT GGTTACACAACAAAGTCTGTACCAACCACCTATGTAACCACTTTGGCTCCAAGTGCACCA GTAACTCCTGCCACTAATGCCGTACCAACTACAATAACCACTACTGAATGTTCTGCTGCT ACAAACGCTGCCGGTGAAACTACATCTGTATGCTCTGCTAAGACTATCGTAAGTTCTGCA AGCGCAGGCGAAAACACTGCACCTTCGGCTACCACCCCTGTCACGACGGCTATTCCAACC ACAGTTATTACCACTGAGTCATCTGTTGGTACTAACTCCGCTGGCGAAACAACAACTGGT TACACAACCAAGTCCATCCCAACCACTTACATAACCACTTTGATTCCAGGTTCAAATGGT GCCAAGAATTACGAAACTGTGGCCACAGCAACCAACCCTATTTCAATCAAGACTACATCC CAACTAGCTACAACAGCTTCTGCTTCTAGCGTGGCTCCCGTTGTCACATCTCCATCTCTA ACTGGTCCACTACAATCTGCTTCTGGTTCTGCAGTCGCTACATACTCTGTTCCTTCTATC TCGAGTACTTACCAAGGTGCTGCTAATATCAAGGTTCTTGGAAACTTTATGTGGTTGCTA CTCGCTCTTCCAGTTGTATTCTAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues1367
Protein Molecular Weight136108.91
Protein Theoretical pINot Available
PDB Fileshow
Signalling Regions
  • 1-21
Transmembrane RegionsNot Available
Protein Sequence>Flocculation protein FLO11 MQRPFLLAYLVLSLLFNSALGFPTALVPRGSSEGTSCNSIVNGCPNLDFNWHMDQQNIMQ YTLDVTSVSWVQDNTYQITIHVKGKENIDLKYLWSLKIIGVTGPKGTVQLYGYNENTYLI DNPTDFTATFEVYATQDVNSCQVWMPNFQIQFEYLQGSAAQYASSWQWGTTSFDLSTGCN NYDNQGHSQTDFPGFYWNIDCDNNCGGTKSSTTTSSTSESSTTTSSTSESSTTTSSTSES STTTSSTSESSTSSSTTAPATPTTTSCTKEKPTPPTTTSCTKEKPTPPHHDTTPCTKKKT TTSKTCTKKTTTPVPTPSSSTTESSSAPVPTPSSSTTESSSAPVTSSTTESSSAPVPTPS SSTTESSSAPVTSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPVTSSTTESSSA PVTSSTTESSSAPVTSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPVTSSTTES SSAPVPTPSSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPAPTPSSSTTESSSA PVTSSTTESSSAPVPTPSSSTTESSSTPVTSSTTESSSAPVPTPSSSTTESSSAPVPTPS SSTTESSSAPAPTPSSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPVPTPSSST TESSSAPVPTPSSSTTESSSAPVTSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSA PVPTPSSSTTESSSAPVPTPSSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPVP TPSSSTTESSSAPVPTPSSSTTESSVAPVPTPSSSSNITSSAPSSTPFSSSTESSSVPVP TPSSSTTESSSAPVSSSTTESSVAPVPTPSSSSNITSSAPSSIPFSSTTESFSTGTTVTP SSSKYPGSQTETSVSSTTETTIVPTKTTTSVTTPSTTTITTTVCSTGTNSAGETTSGCSP KTVTTTVPTTTTTSVTTSSTTTITTTVCSTGTNSAGETTSGCSPKTITTTVPCSTSPSET ASESTTTSPTTPVTTVVSTTVVTTEYSTSTKPGGEITTTFVTKNIPTTYLTTIAPTPSVT TVTNFTPTTITTTVCSTGTNSAGETTSGCSPKTVTTTVPCSTGTGEYTTEATTLVTTAVT TTVVTTESSTGTNSAGKTTTGYTTKSVPTTYVTTLAPSAPVTPATNAVPTTITTTECSAA TNAAGETTSVCSAKTIVSSASAGENTAPSATTPVTTAIPTTVITTESSVGTNSAGETTTG YTTKSIPTTYITTLIPGSNGAKNYETVATATNPISIKTTSQLATTASASSVAPVVTSPSL TGPLQSASGSAVATYSVPSISSTYQGAANIKVLGNFMWLLLALPVVF
References
External Links
ResourceLink
Saccharomyces Genome Database FLO11
Uniprot IDP08640
Uniprot NameFLO11
PDB ID
4UYR
General ReferenceNot Available