Copper(2+) (YMDB00207)

Identification
YMDB IDYMDB00207
NameCopper(2+)
SpeciesSaccharomyces cerevisiae
StrainBaker's yeast
DescriptionCopper, also known as cu(ii) or copper (II) ion, belongs to the class of inorganic compounds known as homogeneous transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom. Copper is a weakly acidic compound (based on its pKa). Copper exists in all living species, ranging from bacteria to humans. Copper is a potentially toxic compound.
Structure
Thumb
MOLSDFPDBSMILESInChI
Synonyms
  • COPPER (II) ION
  • copper, ion (Cu2+)
  • copper(II) cation
  • Cu(2+)
  • Cu(II)
  • Cu2+
  • cupric ion
  • Cu
CAS number15158-11-9
WeightAverage: 63.546
Monoisotopic: 62.929601079
InChI KeyJPVYNHNXODAKFH-UHFFFAOYSA-N
InChIInChI=1S/Cu/q+2
IUPAC Namecopper(2+) ion
Traditional IUPAC Namecopper(2+) ion
Chemical FormulaCu
SMILES[Cu++]
Chemical Taxonomy
Description belongs to the class of inorganic compounds known as homogeneous transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom.
KingdomInorganic compounds
Super ClassHomogeneous metal compounds
ClassHomogeneous transition metal compounds
Sub ClassNot Available
Direct ParentHomogeneous transition metal compounds
Alternative ParentsNot Available
Substituents
  • Homogeneous transition metal
Molecular FrameworkNot Available
External Descriptors
Physical Properties
StateNot Available
Charge2
Melting pointNot Available
Experimental Properties
PropertyValueReference
Water SolubilityNot AvailablePhysProp
LogPNot AvailablePhysProp
Predicted Properties
PropertyValueSource
logP0.16ChemAxon
pKa (Strongest Acidic)3.09ChemAxon
Physiological Charge2ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 ŲChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m³·mol⁻¹ChemAxon
Polarizability1.78 ųChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Biological Properties
Cellular Locations
  • Cytoplasm, Golgi Apparatus
Organoleptic PropertiesNot Available
SMPDB Pathways
Oxidative phosphorylationPW002461 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG Pathways
Oxidative phosphorylationec00190 Map00190
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Concentrations
Intracellular Concentrations
Intracellular ConcentrationSubstrateGrowth ConditionsStrainCitation
0.01 ± 0.0 µM YPD mediumaerobicBaker's yeastPMID: 10221913
Conversion Details Here
Extracellular Concentrations
Intracellular ConcentrationSubstrateGrowth ConditionsStrainCitation
1 ± 0 µM hops, malted barleyanaerobicBaker's yeastAlcoholic beverage, beer, regular, all - U.S. Department of Agriculture, Agricultural Research Service. 2010. USDA National Nutrient Database for Standard Reference, Release 23. Nutrient Data Laboratory Home Page
2 ± 0 µM grape juiceanaerobicBaker's yeastAlcoholic beverage, wine, table, red - U.S. Department of Agriculture, Agricultural Research Service. 2010. USDA National Nutrient Database for Standard Reference, Release 23. Nutrient Data Laboratory Home Page
Conversion Details Here
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyView
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-03di-9000000000-59c652eccc13cc365f65JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-03di-9000000000-59c652eccc13cc365f65JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-03di-9000000000-59c652eccc13cc365f65JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-03di-9000000000-9acd78ab9faeb89677a7JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-03di-9000000000-9acd78ab9faeb89677a7JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-03di-9000000000-9acd78ab9faeb89677a7JSpectraViewer
References
References:
  • UniProt Consortium (2011). "Ongoing and future developments at the Universal Protein Resource." Nucleic Acids Res 39:D214-D219.21051339
  • Alcoholic beverage, beer, regular, all - U.S. Department of Agriculture, Agricultural Research Service. 2010. USDA National Nutrient Database for Standard Reference, Release 23. Nutrient Data Laboratory Home Page
  • Alcoholic beverage, wine, table, red - U.S. Department of Agriculture, Agricultural Research Service. 2010. USDA National Nutrient Database for Standard Reference, Release 23. Nutrient Data Laboratory Home Page
  • Rae, T. D., Schmidt, P. J., Pufahl, R. A., Culotta, V. C., O'Halloran, T. V. (1999). "Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase." Science 284:805-808.10221913
Synthesis Reference:Not Available
External Links:
ResourceLink
CHEBI ID29036
HMDB IDHMDB0000657
Pubchem Compound ID27099
Kegg IDC00070
ChemSpider ID21864924
FOODB IDFDB030749
WikipediaCopper
BioCyc IDCU+2

Transporters

Protein Details
1. Copper-transporting ATPase
General function:
Involved in nucleotide binding
Specific function:
Probably involved in copper transport and in the regulation of cellular copper level. Retrieves copper from the metallochaperone ATX1 and incorporates it into trans-Golgi vesicles
Gene Name:
CCC2
Uniprot ID:
P38995
Molecular weight:
109828.0
Reactions
ATP + H(2)O + Cu(2+)(In) → ADP + phosphate + Cu(2+)(Out).
Protein Details
2. Probable copper-transporting ATPase
General function:
Involved in nucleotide binding
Specific function:
Probably involved in copper transport and in the regulation of cellular copper level
Gene Name:
PCA1
Uniprot ID:
P38360
Molecular weight:
131838.0
Reactions
ATP + H(2)O + Cu(2+)(In) → ADP + phosphate + Cu(2+)(Out).
ATP + H2O + Cd2+/in → ADP + phosphate + Cd2+/out