Butanoate metabolism
| Source | ID | Pathway |
|---|---|---|
| KEGG | 00650 |  |
Pathway Metabolites
| YMDB ID | Name CAS Number | IUPAC Name | Formula Weight | Structure |
|---|---|---|---|---|
| YMDB00101 | Fumaric acid 110-17-8 | (2E)-but-2-enedioic acid | C4H4O4 116.0722 |  |
| YMDB00153 | Oxoglutaric acid 328-50-7 | 2-oxopentanedioic acid | C5H6O5 146.0981 |  |
| YMDB00175 | Pyruvic acid 127-17-3 | 2-oxopropanoic acid | C3H4O3 88.0621 |  |
| YMDB00236 | Succinic acid semialdehyde 692-29-5 | 4-oxobutanoic acid | C4H6O3 102.0886 |  |
| YMDB00271 | L-Glutamic acid 56-86-0 | (2S)-2-aminopentanedioic acid | C5H9NO4 147.1293 |  |
| YMDB00312 | Acetyl-CoA 72-89-9 | {[(2R,3S,4R,5R)-2-({[({[(3R)-3-[(2-{[2-(acetylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acid | C23H38N7O17P3S 809.571 |  |
| YMDB00335 | gamma-Aminobutyric acid 56-12-2 | 4-aminobutanoic acid | C4H9NO2 103.1198 |  |
| YMDB00338 | Succinic acid 110-15-6 | butanedioic acid | C4H6O4 118.088 |  |
| YMDB00367 | Diacetyl 431-03-8 | butane-2,3-dione | C4H6O2 86.0892 |  |
| YMDB00381 | Thiamine pyrophosphate 154-87-0 | 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium | C12H19N4O7P2S 425.314 |  |
| YMDB00394 | 2-Acetolactate | 2-hydroxy-2-methyl-3-oxobutanoic acid | C5H8O4 132.1146 |  |
| YMDB00410 | (R)-Acetoin 53584-56-8 | (3R)-3-hydroxybutan-2-one | C4H8O2 88.1051 |  |
| YMDB00413 | (R,R)-butane-2,3-diol 24347-58-8 | (2R,3R)-butane-2,3-diol | C4H10O2 90.121 |  |
| YMDB00529 | acetoacetyl-CoA 1420-36-6 | {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl-3-{[2-({2-[(3-oxobutanoyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid | C25H40N7O18P3S 851.607 |  |
| YMDB00708 | 3-Hydroxy-3-methylglutaryl-CoA 1553-55-5 | 5-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido}ethyl)sulfanyl]-3-hydroxy-3-methyl-5-oxopentanoic acid | C27H44N7O20P3S 911.659 |  |
| YMDB00872 | (S)-3-hydroxy-3-methylglutaryl-CoA 1553-55-5 | (3S)-5-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido}ethyl)sulfanyl]-3-hydroxy-3-methyl-5-oxopentanoic acid | C27H44N7O20P3S 911.659 |  |
| YMDB00992 | succinate semialdehyde 692-29-5 | C4H6O3 102.0886 |  | |
| YMDB01038 | fumarate(2-) 110-17-8 | C4H2O4 114.0563 |  | |
| YMDB01053 | pyruvate 127-17-3 | C3H3O3 87.0541 |  | |
| YMDB01386 | 1-Butanol 71-36-3 | butan-1-ol | C4H10O 74.1216 |  |
| YMDB01392 | butanoic acid 107-92-6 | butanoic acid | C4H8O2 88.1051 |  |
Pathway Proteins
| Uniprot ID | Gene Name Locus | Name | Type | Metabolites |
|---|---|---|---|---|
| P41338 | ERG10 YPL028W | Acetyl-CoA acetyltransferase | Enzyme | |
| P54839 | ERG13 YML126C | Hydroxymethylglutaryl-CoA synthase | Enzyme | |
| P39713 | BDH2 YAL061W | Probable diacetyl reductase [(R)-acetoin forming] 2 | Enzyme | |
| P39714 | BDH1 YAL060W | Diacetyl reductase [(R)-acetoin forming] | Enzyme | |
| P17649 | UGA1 YGR019W | 4-aminobutyrate aminotransferase | Enzyme | |
| P16387 | PDA1 YER178W | Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial | Enzyme | |
| P32473 | PDB1 YBR221C | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | Enzyme | |
| P07342 | ILV2 YMR108W | Acetolactate synthase catalytic subunit, mitochondrial | Enzyme | |
| P38067 | UGA2 YBR006W | Succinate-semialdehyde dehydrogenase [NADP+] | Enzyme | |
| Q04792 | GAD1 YMR250W | Glutamate decarboxylase | Enzyme |