LysoPC(16:1(9Z)) (YMDB02210)

Identification
YMDB IDYMDB02210
NameLysoPC(16:1(9Z))
SpeciesSaccharomyces cerevisiae
StrainBrewer's yeast
DescriptionLysoPC(16:1(9Z)) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. Lysophosphatidylcholines can have different combinations of fatty acids of varying lengths and saturation attached at the C-1 (sn-1) position. Fatty acids containing 16, 18 and 20 carbons are the most common. LysoPC(16:1(9Z)), in particular, consists of one chain of palmitoleic acid at the C-1 position. The palmitoleic acid moiety is derived from animal fats and vegetable oils. Lysophosphatidylcholine is found in small amounts in most tissues. It is formed by hydrolysis of phosphatidylcholine by the enzyme phospholipase A2, as part of the de-acylation/re-acylation cycle that controls its overall molecular species composition. It can also be formed inadvertently during extraction of lipids from tissues if the phospholipase is activated by careless handling.
Structure
Thumb
MOLSDFPDBSMILESInChI
Synonyms
  • 1-palmitoleoyl-glycero-3-phosphocholine
  • LPC(16:1)
  • LPC(16:1/0:0)
  • LPC(16:1n7/0:0)
  • LPC(16:1w7/0:0)
  • LyPC(16:1)
  • LyPC(16:1/0:0)
  • LyPC(16:1n7/0:0)
  • LysoPC(16:1)
  • LysoPC(16:1/0:0)
  • LysoPC(16:1n7/0:0)
  • LysoPC(16:1w7/0:0)
  • Lysophosphatidylcholine(16:1)
  • Lysophosphatidylcholine(16:1/0:0)
  • Lysophosphatidylcholine(16:1n7/0:0)
  • Lysophosphatidylcholine(16:1w7/0:0)
  • LyPC(16:1w7/0:0)
  • 1-(9Z-Hexadecenoyl)-sn-glycero-3-phosphocholine
  • 1-Palmitoleoyl-glycero-3-phosphocholine
  • 1-Palmitoleoyl-glycerophosphocholine
  • 1-Palmitoleoyl-GPC
  • GPC(16:1(9Z))
  • GPC(16:1)
  • LPC 16:1(9Z)/0:0
  • LPC(16:1(9Z)/0:0)
  • LysoPC 16:1(9Z)/0:0
  • Lysophosphatidylcholine(16:1(9Z)/0:0)
  • PC 16:1(9Z)/0:0
  • PC(16:1(9Z)/0:0)
  • LPC(16:1)
  • LPC(16:1/0:0)
  • LPC(16:1n7/0:0)
  • LPC(16:1W7/0:0)
  • LyPC(16:1)
  • LyPC(16:1/0:0)
  • LyPC(16:1n7/0:0)
  • LysoPC a C16:1
  • LysoPC(16:1)
  • LysoPC(16:1/0:0)
  • LysoPC(16:1n7/0:0)
  • LysoPC(16:1W7/0:0)
  • Lysophosphatidylcholine(16:1)
  • Lysophosphatidylcholine(16:1/0:0)
  • Lysophosphatidylcholine(16:1n7/0:0)
  • Lysophosphatidylcholine(16:1W7/0:0)
  • LysoPC(16:1(9Z))
  • 1-(9Z-Hexadecenoyl)-glycero-3-phosphocholine
  • 1-Palmitoleoylglycerophosphocholine
  • 1-Palmitoleoyl-lysophosphatidylcholine
  • 1-Palmitoleoyl-sn-glycero-3-phosphocholine
  • GPC(16:1(9Z)/0:0)
  • GPC(16:1n7)
  • GPC(16:1n7/0:0)
  • GPC(16:1W7)
  • GPC(16:1W7/0:0)
  • LPC(16:1(9Z))
  • LPC(16:1n7)
  • LPC(16:1W7)
  • LysoPC(16:1n7)
  • LysoPC(16:1W7)
  • Lysophosphatidylcholine(16:1(9Z))
  • Lysophosphatidylcholine(16:1n7)
  • Lysophosphatidylcholine(16:1W7)
  • LysoPC(16:1(9Z)/0:0)
CAS numberNot Available
WeightAverage: 493.6142
Monoisotopic: 493.316839407
InChI KeyLFUDDCMNKWEORN-HSZRJFAPSA-N
InChIInChI=1S/C24H48NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)30-21-23(26)22-32-33(28,29)31-20-19-25(2,3)4/h10-11,23,26H,5-9,12-22H2,1-4H3/t23-/m1/s1
IUPAC Name(2-{[(2R)-3-[(9Z)-hexadec-9-enoyloxy]-2-hydroxypropyl phosphono]oxy}ethyl)trimethylazanium
Traditional IUPAC Name(2-{[(2R)-3-[(9Z)-hexadec-9-enoyloxy]-2-hydroxypropyl phosphono]oxy}ethyl)trimethylazanium
Chemical FormulaC24H48NO7P
SMILESCCCCCCC=CCCCCCCCC(=O)OC[C@@H](O)COP([O-])(=O)OCC[N+](C)(C)C
Chemical Taxonomy
Description belongs to the class of organic compounds known as 1-acyl-sn-glycero-3-phosphocholines. These are glycerophosphocholines in which the glycerol is esterified with a fatty acid at O-1 position, and linked at position 3 to a phosphocholine.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassGlycerophospholipids
Sub ClassGlycerophosphocholines
Direct Parent1-acyl-sn-glycero-3-phosphocholines
Alternative Parents
Substituents
  • 1-acyl-sn-glycero-3-phosphocholine
  • Phosphocholine
  • Fatty acid ester
  • Dialkyl phosphate
  • Organic phosphoric acid derivative
  • Phosphoric acid ester
  • Alkyl phosphate
  • Fatty acyl
  • Tetraalkylammonium salt
  • Quaternary ammonium salt
  • Secondary alcohol
  • Carboxylic acid ester
  • Carboxylic acid derivative
  • Monocarboxylic acid or derivatives
  • Organic oxide
  • Organooxygen compound
  • Organonitrogen compound
  • Organic nitrogen compound
  • Alcohol
  • Organic oxygen compound
  • Organopnictogen compound
  • Carbonyl group
  • Organic salt
  • Amine
  • Hydrocarbon derivative
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Physical Properties
StateSolid
Charge0
Melting pointNot Available
Experimental Properties
PropertyValueReference
Water SolubilityNot AvailablePhysProp
LogPNot AvailablePhysProp
Predicted Properties
PropertyValueSource
Water Solubility0.00043 g/LALOGPS
logP1.72ALOGPS
logP0.83ChemAxon
logS-6.1ALOGPS
pKa (Strongest Acidic)1.86ChemAxon
pKa (Strongest Basic)-3.4ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area105.12 ŲChemAxon
Rotatable Bond Count23ChemAxon
Refractivity143.39 m³·mol⁻¹ChemAxon
Polarizability56.45 ųChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Biological Properties
Cellular LocationsNot Available
Organoleptic PropertiesNot Available
SMPDB Pathways
Lysolipid incorporation into ER PC(16:1(9Z)/16:1(9Z))PW002785 ThumbThumb?image type=greyscaleThumb?image type=simple
Lysolipid incorporation into Mitochondria PC(16:1(9Z)/16:1(9Z))PW002793 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Concentrations
Intracellular Concentrations
Intracellular ConcentrationSubstrateGrowth ConditionsStrainCitation
0.443 ± 0.02215 µM YEB media with 0.5 mM glucoseaerobicBrewer's yeastExperimentally Determined
Not Available
664000 ± 57825 umol/L SD media with 2% raffinose24 oCBY4741PMID: 19174513
394250 ± 7875 umol/L SD media with 2% raffinose37 oCBY4741PMID: 19174513
Conversion Details Here
Extracellular ConcentrationsNot Available
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyView
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (1 TMS) - 70eV, Positivesplash10-009i-9421000000-8369cf40512bb91f9a92JSpectraViewer
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, PositiveNot AvailableJSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-0udi-0000190000-3b2f823b3cd8feb26a69JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-0udo-0002990000-7176cdf7186de27b5716JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0j4l-0309300000-27e1bde7aced3e495eafJSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-002f-0000900000-20d8b47f384d6c6abc9dJSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-001l-0900600000-d81e90dde6012dc43928JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0fai-0910400000-7b25c82c4a89b9527428JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-0006-0030900000-f418d5b39662ed44b8b0JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-0udi-1090100000-eb1b8f27f35b0db065eeJSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-0udi-1090000000-e8497356b3a95210d3f6JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-004i-0000190000-d207603b0418f8cc497dJSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-0ufr-0090070000-848973b728ef1ffc0d69JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-0udi-0090020000-121fe6e93b0d8bcfe171JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-014i-0000190000-fa3d2231e19f49a461abJSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-0aor-0001960000-6bdc0b97b839b55840eeJSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0pcr-1609710000-c34b47c99b7f3709e023JSpectraViewer
1D NMR13C NMR SpectrumNot AvailableJSpectraViewer
1D NMR1H NMR SpectrumNot AvailableJSpectraViewer
1D NMR13C NMR SpectrumNot AvailableJSpectraViewer
1D NMR1H NMR SpectrumNot AvailableJSpectraViewer
1D NMR13C NMR SpectrumNot AvailableJSpectraViewer
1D NMR1H NMR SpectrumNot AvailableJSpectraViewer
1D NMR13C NMR SpectrumNot AvailableJSpectraViewer
1D NMR1H NMR SpectrumNot AvailableJSpectraViewer
1D NMR13C NMR SpectrumNot AvailableJSpectraViewer
1D NMR1H NMR SpectrumNot AvailableJSpectraViewer
1D NMR13C NMR SpectrumNot AvailableJSpectraViewer
1D NMR1H NMR SpectrumNot AvailableJSpectraViewer
1D NMR13C NMR SpectrumNot AvailableJSpectraViewer
1D NMR1H NMR SpectrumNot AvailableJSpectraViewer
1D NMR13C NMR SpectrumNot AvailableJSpectraViewer
1D NMR1H NMR SpectrumNot AvailableJSpectraViewer
1D NMR13C NMR SpectrumNot AvailableJSpectraViewer
1D NMR1H NMR SpectrumNot AvailableJSpectraViewer
1D NMR13C NMR SpectrumNot AvailableJSpectraViewer
1D NMR1H NMR SpectrumNot AvailableJSpectraViewer
References
References:Not Available
Synthesis Reference:Not Available
External Links:
ResourceLink
CHEBI ID73851
HMDB IDHMDB10383
Pubchem Compound ID24779461
Kegg IDC04230
ChemSpider ID24766525
FOODB IDFDB027534
Wikipedia IDNot Available
BioCyc IDNot Available